Healthy bone tissue “can be seen as a physiological hub of several stimuli of different origin (ie. dietary, endocrine, nervous, immune, skeletal muscle traction, biomechanical load).” Osteoporosis can develop with an imbalance in one or more of these aspects leading to a decrease in bone mineral density and bone mass and changing the structure and strength of bone tissue.

 

7-dehydrocholesterol

“7-dehydrocholesterol present in the skin is the basic raw material for the synthesis of vitamin D. 7-dehydrocholesterol is broken down to produce the pre-D isomers upon exposure to ultraviolet light B. The pre-D isomers, in non-catalytic process, get rapidly converted to vitamin D₃ (Cholecalciferol).” https://www.sciencedirect.com/science/article/abs/pii/S0083672921000455

 

Alcohol

“Some of the risk factors for osteoporosis are non-modifiable, including age, sex, genetic background, and underlying illness, while others are modifiable, for instance smoking, diet, exercise, medication, body mass index (BMI), and heavy alcohol drinking.” https://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4014

 

Calcitriol

“Calcitriol, a hormone that’s also known as active vitamin D, helps to increase the amount of calcium your gut can absorb from the food you eat and release it into your bloodstream. Calcitriol also prevents calcium loss from your kidneys. Parathyroid hormone is responsible for stimulating the enzyme that transforms vitamin D your skin makes from sun exposure into calcitriol.”

https://my.clevelandclinic.org/health/articles/22330-calcitonin

 

Calcitonin

Calcitonin is a hormone that your thyroid gland makes and releases to help regulate calcium levels in your blood by decreasing it. Calcitonin opposes the actions of the parathyroid hormone, which is a hormone that increases your blood calcium levels.” https://my.clevelandclinic.org/health/articles/22330-calcitonin

 

Calcium

“Almost all (98%) calcium in the body is stored in the bones, and the body uses the bones as a reservoir for, and source of, calcium to maintain calcium homeostasis.” https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/

 

Cigarette smoke

“Some of the risk factors for osteoporosis are non-modifiable, including age, sex, genetic background, and underlying illness, while others are modifiable, for instance smoking, diet, exercise, medication, body mass index (BMI), and heavy alcohol drinking.” https://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4014

 

Collagenous Fibre

“Bone consists of highly calcified, intercellular bone matrix, and three types of cells—osteocytes, osteoblasts, and osteoclasts. The outer surface of bone is covered by periosteum,  which is bound to bone by bundles of collagen fibers…”

 

Collagen, Type I

 

Cortisol

“The prevalence of osteoporosis due to endogenous cortisol excess has been reported to be 50–59% and about one-third to half of patients with hypercortisolemia-induced osteoporosis experience fragility fracture.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330848/

 

Estrogen

Estrogen receptors (ERs) are highly expressed in osteoblasts, osteoclasts, and osteocytes, offering protective effects in bone. … The net effects of estrogen deficiency are increased bone turnover and enhanced bone resorption, which result in osteoporosis.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836058/

 

Hydroxyapatite

65% of bone tissue is inorganic mineral largely calcium and phosphorus in the form of an insoluble salt called hydroxyapatite.

 

Iodine

“Iodine is a crucial micronutrient for thyroid hormone synthesis and the only source is dietary.” https://www.sciencedirect.com/science/article/pii/B9780128021682000129

 

Magnesium

 

Menopause

While osteoporosis and risk of fracture or break can affect anyone, it commonly occurs with aging especially for post-menopausal women.

 “Post-menopausal osteoporosis is caused by increased activity of osteoclasts, related to decreased levels of estrogen in the circulation. Lack of estrogen is associated with an increased release of cytokines, such as interleukin (IL)-1 and IL-6, which stimulate osteoclasts.”  https://www.sciencedirect.com/topics/medicine-and-dentistry/primary-osteoporosis

 

Osteoporosis

 

Osteoclasts

Bone remodeling occurs in different parts of the body throughout life to maintain bone architecture balance and systemic mineral homeostasis. During this "remodeling" process, osteoclasts remove mineralized bones, whereas osteoblasts form new bones. These resorption and formation phases are linked and balanced with intermittent coupling phases.” https://www.sciencedaily.com/releases/2022/02/220224091005.htm

 

Osteoblasts

 

Osteocytes

“Osteoblasts are bone-forming cell, osteoclasts resorb or break down bone, and osteocytes are mature bone cells. An equilibrium between osteoblasts and osteoclasts maintains bone tissue.”  https://training.seer.cancer.gov/anatomy/skeletal/tissue.html

 

Phosphorus

 

Potassium

 

Parathyroid Hormone (PTH)

“Parathyroid hormone (PTH) is a hormone that your parathyroid glands make and release to control the level of calcium in your blood by increasing it. PTH also helps control the levels of phosphorus (a mineral) and vitamin D (a hormone) in your blood and bones. You have four pea-sized parathyroid glands located behind your thyroid gland.” https://my.clevelandclinic.org/health/articles/22330-calcitonin

 

Periosteum

The outer surface of bone is covered by periosteum, which is bound to bone by bundles of collagen fibers.

 

Proteoglycans

“Proteoglycans play important roles in organizing the bone ECM (extra cellular matrix)...” https://pubmed.ncbi.nlm.nih.gov/17621645/

 

Sodium

 

Sunlight – UV B radiation

Sunlight, in particular UVB between the wavelengths of 290 and 315 nm, is the main source for producing vitamin D in the skin and is the primary source of vitamin D for the body. It is estimated that 90% of the daily body requirements are met by sunlight exposure.”  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846322/

 

T3 Triiodothyronine

In adults, T(3) regulates bone turnover and bone mineral density https://pubmed.ncbi.nlm.nih.gov/19885809/

 

T4 Thyroxine

 

Thyroid-stimulating hormone (TSH)  

“Thyroid-stimulating hormone, commonly called TSH and also referred to as thyrotropin, is a hormone that your pituitary gland releases to trigger your thyroid to produce and release its own hormones — thyroxine (T4) and triiodothyronine (T3).” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230461/

 

Testosterone

 

Vitamin D3

Without enough vitamin D, one can't form enough of the hormone calcitriol (known as the “active vitamin D”).  This in turn leads to insufficient calcium absorption from the diet. In this situation, the body must take calcium from its stores in the skeleton, which weakens existing bone and prevents the formation of strong, new bone.”  https://www.bones.nih.gov/health-info/bone/bone-health/nutrition/calcium-and-vitamin-d-important-every-age

Quantity: 30 Vials 

Model: OST

Note: Ergopathics test kits are not intended to diagnose, prevent, treat or cure any disease, disorder or abnormal physical state.  The vials contain ethanol and water and the process used to imprint them with electromagnetic signatures has not been tested or validated by any scientific method and is not approved by any regulatory authority. They are intended for use solely by qualified providers to support wellness and manage stress.